F-statistics suggest that Le Piage II is genetically intermediate between Fournol 85 and El Mirn (Supplementary Data 2.D). 581582, 128163 (2021). Key, F. M. et al. The grouping of Epigravettian-associated populations is shown with the same colour in a. 6 and Supplementary Fig. After a period of limited admixture that spanned the beginning of the Mesolithic, we find genetic interactions between western and eastern European hunter-gatherers,who were also characterized by marked differences in phenotypically relevant variants. Nakatsuka, N. et al. 2, e190 (2006). Tina has 11 jobs listed on their profile. Purchasing this course makes it your own. Protoc. Quat. How to Become a Data Scientist at FAANG (Ft. Tina Huang) In this video, I had the opportunity to talk with Tina Huang, a Data Scientist at one of the FAANG companies. Nat. Subsequently, I worked in bioinformatics for a year and then did my Masters in computer science (MCIT) at the University of Pennsylvania. Complete mitochondrial genome sequence of a Middle Pleistocene cave bear reconstructed from ultrashort DNA fragments. Herein, methane is upgraded through the photocatalytic oxidative coupling of methane (OCM) over a ternary Ag-AgBr/TiO 2 catalyst in a pressurized flow reactor. The mapped reads from the same individual and library set-up were merged and duplications were removed with DeDup. USA 117, 1279112798 (2020). Article Last Name Huang #8. These data cover a time span of around 30,000 years from the Upper Palaeolithic to the Late Neolithic (defined here by the presence of pottery rather than by farming subsistence economy if not indicated), derive from multiple prehistoric cultural contexts, and originate from 54 archaeological sites in 14 countries: 1 Aurignacian-associated individual from Belgium and 1 culturally unassigned individual from Romania (3533ka), 15 Gravettian-associated individuals from Spain, France, Belgium, Czechia and Italy (3126ka), 2 Solutrean-associated individuals from Spain and France (2321ka), 9 Magdalenian-associated individuals from France, Germany, and Poland (1815ka), 4 Epigravettian-associated individuals from Italy (1713ka), 2 Federmesser-associated individuals from Germany (14ka), and 81 Mesolithic to Neolithic foragers from across western Eurasia (115ka), together with 1 central Eurasian Neolithic individual from Tajikistan (8ka) (Fig. Ancient Rome: A genetic crossroads of Europe and the Mediterranean. The cleaned reads with base quality and mapping quality over 30 were piled up with mpileup in SAMtools 1.373 on the 1240k targeted sites. 803147-RESOLUTION (to S.T. Radiocarbon 55, 163177 (2013). Google Scholar. The tentative placements of low-coverage ancient individuals based on their haplogroup assignment (Supplementary Data 1.A) are indicated with arrows on the respective branches. Kumar, S., Stecher, G., Li, M., Knyaz, C. & Tamura, K. MEGA X: molecular evolutionary genetics analysis across computing platforms. Write a sharp and effective resume in minutes and get noticed by employers. Reducing microbial and human contamination in DNA extractions from ancient bones and teeth. Tina Huang, a data scientist currently working at a FAANG (Facebook, Amazon, Apple, Netflix, and Google Alphabet) company. 44, W58W63 (2016). Lifetime access to all course materials and updates. The mitochondrial haplogroups were determined using HaploGrep 295, based on the consensus sequences generated from Schmutzi inspected for each sample at increasing quality filters (from q0 to q20). Its like the different ingredients in your recipe. Both double-stranded and single-stranded libraries were further amplified with IS5/IS6 primers to reach a concentration of 200400ng/l as measured on a NanoDrop spectrophotometer (Thermo Fisher Scientific). We generated genome-wide sequencing data for 102 newly reported hunter-gatherers, and increased coverage for 14 previously published individuals4. Limits of long-term selection against Neandertal introgression. All remains were sampled with the approval of the institutions responsible for the analysis of archaeological material. Natl Acad. 724703 and no. With a lot of raw data, you need to put in some work. Connect with them: Email: hellotinah@gmail.com. You need a lot of information to predict whats going to happen, but then you also need a lot of information to make decisions about what youre going to do. Google Scholar. Hi, my name is Tina and I'm a data scientist at a FAANG company. In the MDS plot, we find that all of the newly and previously reported Epigravettian-associated individuals fall within the Villabruna cluster4 (Fig. The end goal is to create and grow a product that users love. Data warehousing is a relatively new field that focuses on the use of large datasets for analytical purposes. The generation time is set to 29 years and the error bars show the SE of the admixture date estimated from jackknife resampling (n=22 autosomal chromosomes). Jones, E. R. et al. Dots are maximum likelihood estimates and error bars show 95% confidence intervals of the derived allele frequencies (n, the number of individuals in each group, is provided in Supplementary Data 3.G). Genome Biol. Write for us- Weird Science, Energy & Minerals Guest Post. 39, msac017 (2022). Here we analyse 356 ancient hunter-gatherer genomes, including new genomic data for 116 individuals from 14 countries in western and central Eurasia, spanning between 35,000 and 5,000 years ago. Each aDNA library was double indexed60 in 14 parallel 100l reactions using PfuTurbo DNA Polymerase (Agilent). Taipei, Taiwan . They, along with it, will be accessible to you indefinitely. Otte, M.) 105160 (Errance, 2013). In her journey of eventually becoming a data scientist, Tina started out with an undergraduate in Pharmacology. and T. Saupe received support from the European Union through the European Regional Development Fund (project no. In addition to her data science work, Tina has also created the popular popular game Code Wars. Proc. T.T., D.C. and E.A. View Tina Zhang's business profile as Brand Specialist at Dymind Biotechnology. Become an in-demand #DataScience professional TODAY with the 365 Data Science Program -> https://365datascience.com, analyzing similar products to compare how they performed, data visualizations with SQL and Python or R. It is often considered as a pan-European cultural mosaic with regional variations in material to symbolic productions20,21. Sikora, M. et al. It just raised $12.2 million. 412, 3743 (2016). ScienceDaily. Tina is a computer science student at Stanford University. Correspondence to 8). Tina Huang, born on October 28, 1981, is an American stage and television actress of Taiwanese descent known for her recurring roles in Rizzoli & Isles and for her semi-regular role as Melinda Trask on the NBC soap Days of Our Lives. All in the name of developing an amazing product! a, The genetic ancestry of hunter-gatherers dated between 14ka and 5.2ka modelled using qpAdm, with Oberkassel, Yuzhniy Oleniy Ostrov, Goyet Q-2 and Neolithic farmers from present-day Turkey (Barcn, Mentee and Boncuklu sites) representing Oberkassel (WHG) (blue), Sidelkino (EHG) (red), GoyetQ2 (orange) and Anatolian Neolithic farmer (green) ancestries, respectively. TV Actress. We visualize the total amount of ROH longer than 4 cM for (a) pre-LGM individuals, (b) Epigravettian- and Magdalenian-associated individuals, (c) individuals carrying high proportions of Sidelkino-related ancestry, and (d) individuals carrying high proportions of Oberkassel-related ancestry. Ancient genome-wide DNA from France highlights the complexity of interactions between Mesolithic hunter-gatherers and Neolithic farmers. You have to deal with large datasets; however, you have to do your work in a way that makes sense to your team. We further tested whether individuals included in the Vstonice and Fournol clusters share similar allele frequencies with the main representatives of those two clusters. Great content - Tina is all class and an excellent instructor. My experience includes an [] These European regions, therefore, constitute climatic refugia where human populations survived during the LGM. 1). Overall, the literature suggests that Chinese Canadian students demonstrate high levels of achievement and that this academic success is associated with factors such as stronger feelings of ethnic identity, better English language skills in the family, Chinese . After 7.5ka, as ANF ancestry had reached regions north of the Alps, individuals carrying a hunter-gatherer genetic profile were primarily restricted to the northern fringes of Europe (Fig. For the DNA lysis, a solution of 900l EDTA, 75l H2O and 25l proteinase K was added. My name is Tina and I'm a data scientist and YouTuber. Conversely, individuals in the Sidelkino cluster are genetically closer to AG3 than Tutkaul 1. Nat. In particular, the 13ka Pradis 1 individual from northeastern Italy represents the most basal lineage compared to all other Epigravettian-associated individuals, including the older Tagliente 2 and Villabruna genomes from northern Italy (group 1). I'm interested in tech, trading, and how to minimize effort and maximize outcome. Mounier, A. et al. 8 Changes of Sidelkino and Oberkassel ancestry proportions in post-14 ka hunter-gatherers. 26 and Supplementary Data 2.H). Subsequently, I worked in . Fu, Q. et al. Upper Palaeolithic genomes reveal deep roots of modern Eurasians. Tina is excellent when it comes to getting overall data science career advice. Cosimo Posth, He Yu, Ayshin Ghalichi, Hlne Rougier, Isabelle Crevecoeur, Yilei Huang, Harald Ringbauer, Adam B. Rohrlach, Kathrin Ngele, Vanessa Villalba-Mouco, Rita Radzeviciute, Tiago Ferraz, Alexander Stoessel, Rezeda Tukhbatova, Dorothe G. Drucker, Martina Lari, Alessandra Modi, Stefania Vai, Tina Saupe, Christiana L. Scheib, Giulio Catalano, Luca Pagani, Sahra Talamo, Helen Fewlass, Laurent Klaric, Andr Morala, Mathieu Ru, Stphane Madelaine, Laurent Crpin, Jean-Baptiste Caverne, Emmy Bocaege, Stefano Ricci, Francesco Boschin, Priscilla Bayle, Bruno Maureille, Foni Le Brun-Ricalens, Jean-Guillaume Bordes, Gregorio Oxilia, Eugenio Bortolini, Olivier Bignon-Lau, Grgory Debout, Michel Orliac, Antoine Zazzo, Vitale Sparacello, Elisabetta Starnini, Luca Sineo, Johannes van der Plicht, Laure Pecqueur, Gildas Merceron, Graldine Garcia, Jean-Michel Leuvrey, Coralie Bay Garcia, Asier Gmez-Olivencia, Marta Potowicz-Bobak, Dariusz Bobak, Mona Le Luyer, Paul Storm, Claudia Hoffmann, Jacek Kabaciski, Tatiana Filimonova, Svetlana Shnaider, Natalia Berezina, Borja Gonzlez-Rabanal, Manuel R. Gonzlez Morales, Ana B. Marn-Arroyo, Beln Lpez, Carmen Alonso-Llamazares, Annamaria Ronchitelli, Caroline Polet, Ivan Jadin, Nicolas Cauwe, Joaquim Soler, Neus Coromina, Isaac Ruf, Richard Cottiaux, Geoffrey Clark, Lawrence G. Straus, Marie-Anne Julien, Silvia Renhart, Dorothea Talaa, Stefano Benazzi, Matteo Romandini, Luc Amkreutz, Herv Bocherens, Christoph Wiing, Sbastien Villotte, Javier Fernndez-Lpez de Pablo, Magdalena Gmez-Puche, Marco Aurelio Esquembre-Bebia, Pierre Bodu, Liesbeth Smits, Bndicte Souffi, Rimantas Jankauskas, Justina Kozakait, Christophe Cupillard, Hartmut Benthien, Kurt Wehrberger, Ralf W. Schmitz, Susanne C. Feine, Tim Schler, Corinne Thevenet, Dan Grigorescu, Friedrich Lth, Andreas Kotula, Henny Piezonka, Franz Schopper, Ji Svoboda, Sandra Szelov, Andrey Chizhevsky, Aleksandr Khokhlov, Nicholas J. Conard, Frdrique Valentin, Katerina Harvati, Patrick Semal, Bettina Jungklaus, Alexander Suvorov, Rick Schulting, Vyacheslav Moiseyev, Kristiina Mannermaa, Alexandra Buzhilova, Thomas Terberger, David Caramelli, Eveline Altena, Wolfgang Haak, Johannes Krause. Tina Huang Data Scientist. This derived ancestrythe Fournol clustersurvived during the LGM in Solutrean-associated individuals, possibly within the Franco-Cantabrian climatic refugium25, leading to later populations associated with the Magdalenian culture (GoyetQ2 cluster and El Mirn). Nat. In this study, we analyse 356 ancient hunter-gatherer genomes including new genomic data of 116 individuals dated to 355ka alongside a novel contamination-estimation method based on runs of homozygosity. Hi friends! The incoming Villabruna ancestry later became the most widespread hunter-gatherer ancestry across Europe. Claim Author Page. Libraries were quantified using the IS7 and IS8 primers59 in a quantification assay using a DyNAmo SYBR Green qPCR Kit (Thermo Fisher Scientific) on the LightCycler 480 (Roche).

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